This Benadryl Itch Relief Stick is moderately effective, depending on what ails you. We've purchased this anti itch stick for numerous ailments over the years. It seems to be most effective for mosquito bites. My daughter is prone to pretty large welts from Mosquitos. This Benadryl anti itch stick is pretty effective at relieving the itch. It's good for children. It doesn't sting, and is slightly cooling. It helps reduce the urge to itch. If it weren't for this product , my daughter would probably end up scratching to the point of bleeding. It's also nice to use something that isn't harsh, strong, or stinging. I also used this when I had hives from an allergic reaction to Penicillin. The hives were pretty intense, and this stick didnt help much at all. I needed oral steroids and Benadryl (much stronger) to help with the intense itching. It also did not help with a rash that my daughter had on the back of her neck when she had lice. She had really bad itching and also needed stronger medication. In summary, this product is nice for mild itching and mild ailments. It doesn't do much for bigger problems.