I bought the Up & Up Multi-Symptom Day Non-drowsy Cold/Flu relief one time when target was out of the Nyquil day tablets I usually take. The ingredients seemed to be pretty comparable, and the price was cheaper, so I figured I had nothing to lose. I have actually replaced the Nyquil DAY with these, because I think they work just as well, if not better and the price is so much cheaper! It works really quickly to help relieve fever, and aches and pains. I would say within in hour my throat will feel better, and my congestion is starting to lessen up. I don't think it really suppresses my coughs, but it does a good job of minimizing it so that I can function without feeling like I am on my deathbed. And it doesn't make me feel like I am in a fog or like I need to lay down and take a nap. I don't necessarily feel energized, but definitely feel like I can make it through whatever I am doing. These are definitely worth giving a try if you aren't feeling too great!