These Thermacare wraps give me the most relief for my back than any other product I've ever tried. I wear them frequently as I have disintegrating discs in my back which causes muscle strain when I walk or stand. I put one on in the morning (it remains hidden underneath my clothing) and I generally get all day relief. You wear it for about eight hours but the relief lasts for at least ten hours after you remove the wrap which gives me relief all day long. I especially love the Extra large size as it covers my entire back, providing relief for the entire back. Once I discovered these, I greatly reduced the amount of pain medication I need to take and when I do need something, the pain is relieved by over the counter medication instead of narcotics. Effectiveness Most of the time, I get relief within ten minutes or so. Ease of Use Very easy to use. Merely remove it from its pouch and wrap around your waist.