This newer cream of the skin ceuticals line is very effective in repairing skin that has lost its elasticity. Although recommended once or twice daily, I have found it to be most effective if used at night when the skin is most likely to repair itself. It is also compatible with other brands so it can be used in combination with other creams as well. Skin ceuticals is a trusted and well tested line of skincare and I have tried many different brands but always seem to return to this line as it yields the most consistent and long term results. Iwould also recommend the eyecream in this same line as it is also effective in erasing fine lines, wrinkles and puffiness around the line. It is best to talk to someone who knows this line well before trying anything without having the knowledge about what you are trying because all products in this line are not suitable for all skin types..