New Chapter really is the best vitamin and supplement brand out there, and I've tried many. Their products are all food-sourced as opposed to artificially engineered or isolated through chemical processing. I take this turmeric supplement regularly for the overall antioxidant benefit. However there are times when I take a higher dose, several times over the course of a day, in order to address specific symptoms. This is something my naturopathic-bent doctor recommended. For back pain (related to nerves and spinal compression issue) I find this product really reduces inflammation and makes me more comfortable after 6-12 hours. I also use a higher medicinal dose for occasional migraine-like headaches and for inflammation of plantar fasciitis. The common thread in all these is essentially that the turmeric is an outstanding natural painkiller and reduces inflammation dramatically. I also know that there's little to no chance of toxicity or damage, as the herb is very safe and supportive of health and immunity.