The Bayer Extra Strength Aspirin is the only aspirin that can live up to its claims. Not only did it help minimize my headaches and migraines but also helped to get rid of them completely. I also really liked the bottle and it opened up easily for me, but not too easily. The bottle itself is small enough to fit in your purse or a first aid kit which I really liked. The only thing I would really change is the fact that I can't seem to find a bigger bottle of this Aspirin and since I live with five other people, it is frequently on our shopping list. Effectiveness It kept my headache away for close to five hours which helped me make it through the work day, and many more that followed. I've used it after an obstacle run before and it helped to ease the pain quite a bit during the next couple of days. Immediacy I felt the Bayer Extra Strength Aspirin kicking in after around ten minutes and kicked in at full strength. I didn't feel any headache pain for five hours.