I have suffered from high cholesterol for years and have controlled it somewhat through diet modulation. However, it never consistently worked so I went on the combination medication vytorin. It has been a godsend as my cholesterol, LDL and tryglycerides are well under control and I am experiencing no side effects whatsoever. It is a daily routine and easy to take. To be sure I do not suffer from side effects such as muscle aches I would recommend taking coenzyme Q10 as a supplement.