My youngest was born 8 weeks early and like many preemies was diagnosed with reflux. He had a grade 4 (the worst). We tried many formulas, and this was by far the best. It was a huge relief to see him enjoying his feedings. The spitup was reduced tremendously after the first couple of days on Enfamil A.R. It was great to see him keeping his formula down. He quickly began gaining weight and is now a Healthy, well adjusted toddler.I personally like the powder formula much better than the liquid in a can. I recommend this formula for any baby who spits up frequently! Thanks Enfamil!!