My husband has been in several tragic accidents, and has had many injuries that cause him constant pain every day. He has tried many different pain relievers to enable himself to do work each day. This medication does much more for him by taking 2 pills per day than Ibuprofin, Tylenol, Aspirin, or any other pain reliever, even when he would take 8 of the others to get them to work. These work great, and are not hard on your organs. We highly recommend these!