Frontline Plus has been a lifesaver.  Lyme disease is a hard reality where we live and people as well as pets can get it.  I use Frontline on both of my girls, year round and don't have problems.  I may occasional see a flea but they don't multiply and I only see a few a year, mostly when they have been around other animals that aren't treated.  I would buy it from my vet until I saw the price difference on dog.com.  I now order tons of stuff on their.  Frontline is the only way to go! Something to remember is not bathe the dog for 24 hours before and 24 hours after.  We have a set day...