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Bupropion sometimes is given to help people stop smoking. Although how this drug works is not clear it's thought that it changes the concentration of some chemicals that are needed for nerve transmission in the brain. I take the smallest dose which is 150 mg.
The side affects include constipation, decreased appetite, diarrhea, dizziness, dry mouth, headache, and insomnia. These may subside after your body gets used to it. I have no side affects that I know of from this drug. I do have dry mouth but I have an autoimmune disorder which causes it. I have taken Wellbutrin (bupropion) for a much longer time than I've had Sjogren's Syndrome.
This may all informative but the purpose of this review is to make people aware that in studies done by The ConsumerLab www.consumerlab.com/results/wellbutrin-bupropion.asp the generic drug, bupropion, worked differently than the non-generic drug Wellbutrin XL. Time-released generic drugs they found sometimes use tablet technologies that differ from the original product. When I brought this study to my doctor he suggested that the tablet coating itself can be different. However he also mentioned the cost of the non-generic drug i.e. health insurers prefer doctors to prescribe generics. There are along with the study anecdotal stories by consumers of symptoms they had when they were switched to the generic drug. Reports of generic drug problems by consumers are posted at ww.peoplespharmacy.com.
Interestingly the FDA doesn't require that generic brands get approval for clinical trials like they do for brand name drugs. The tests on brand name drugs require hundreds if not thousands of people in the test. The agency requires that generic drugs be tested so that there is lab data in three dozen or fewer people that show the drug in the bloodstream seeming to act in a similar way as the brand name.
Jo's Viewpoint
I am fine with the generic formula. It hasn't caused me any problems. I do believe that people should be aware of these substantiated problems with some generic drugs. I don't believe Wellbutrin is the only drug that is affected by the use of the generic formula.
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