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My doctor prescribed Topamax because I was getting terrible migraines and also needed to lose some extra weight. Topamax was great at controlling migraines but I hated the side effects. I found myself forgetting how to say the simplest of words. As a graduate student, this was embarrassing in class when I had to do presentations. I could look at a word, know what it meant but completely forget the pronunciation and these were easy words like "absolutely" and "realistic". I became very forgetful and depressed. It did help me lose weight. I lost about twenty pounds in the month I was taking it. I think part of the reason is it made carbonated beverages taste metallic so I quit drinking sodas. It also made my appetite disappear. However, when I quit taking it, I gained the weight back and then some.