I have tried so many acne products, but Shiseido's Pureness Blemish Gel was the most effective. The 0.5% salicylic acid concentration was the perfect balance for my skin. I have combination skin type with an oily T-zone and normal/dry cheeks. The gel was strong enough to get rid of white heads and acne cysts, but at the same time still gentle enough to not leave an acne scar/dark spot in place of the pimple. I have tried many other products, including products containing Benzoyl Peroxide, and other salicylic acid products including Clinique's Acne Solutions Spot Healing Gel (1.0% salicylic acid concentration). I did not see results with Benzoyl Peroxide products at all, including doctor prescribed medication. The Salicylic acid products were typically too high of a concentration and left dark spots on my skin. The 0.5% of this gel was the perfect balance. In addition, this gel was not as painful as other acne products. It only produced a slight tingling sensation on the skin, not a burning sensation. I saw immediate results within hours of using this gel. The only downside for this product was the price. It is very costly for such a small bottle! Because you will need to apply the gel on the entire surface of your pimple for it to work, the bottle was quickly used up. I recommend this product for those who did not see results with Benzoyl Peroxide, but found other Salicylic Acid products too strong. The 0.5% salicylic acid concentration of this gel was gentle enough yet effective.