Not sure how much of a difference it makes
I have used the Proactiv three step system and used some of the products individually. In general, I think this is the least effective of the three steps. I don't notice any major difference in my skin between when I was using this additional step and when I wasn't. When my skin was getting overly dry and irritated from proactiv, this was the first step that I took out. I think it can be helpful, but in general, the other products already to a good job of removing impurities and smoothing your skin that you may find this step unnecessary. However, if you are using other skincare products and need a decent toner, this one is pretty decent. When I wasn't using it as part of the system, I noticed that it helped me to get an overall smoother look and feel to my skin. It was just too drying to use on a continuous basis. Ease of Application I'm a fan of convenience so I wish this came on presoaked pads or something that didn't require an additional purchase. Side Effects This can be extremely drying to your skin. Immediacy I saw improved skin in less then a week.
Jenjlg
USA