We have been feeding our Great Dane this for 6 years. She was on a chicken based Nutro first then we discovered she was allergic to chicken. So, we switched her to this brand. Great Danes grow for 2 years so it is important that they get a lower protein food. They need to grow slowly. My Dane is almost 7 years old and is very healthy. She has not had any bad health issues. I believe one reason is she has been on the great food for most of her life. It is more expensive but it is well worth it as she is happy and heathy.