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\After having to switch formula after formula after formula and not finding any results, I finally tried Nestle Good Start Supreme with Natual Cultures. I could tell the difference in less than a week! He was not the fussy baby that I was used to and he was spitting up a lot less than he did on other formula. I didn't switch him to this formula until he was 7-8mths old! I really wished I would have started him on it as soon as I stopped breast feeding!!!! I was amazed at the difference the formula made. I suggest this formula over any other formula out there!