Differin is a topical acne gel that works below the surface of your skin to clear acne and prevents new acne from coming. In my experience of using Differin, I have had very positive result as well as a few negative. The main thing is that, after about one month, my acne did start clearing up and after using it for about six months my acne is completely gone. Even though it is very effective and does its job of getting rid of acne there a few downsides to Differin. The first downside is that it does take a little while before it begins working and to make things worse, before it starts working, your acne may actually get a little bit worse. This only does last for about a week or two, though, in my experience. The second, and last, downside is that at the beginning your does burn and irritate your skin slightly. This also only last for a couple of weeks though. All and all, even with the few negatives, I highly recommend Differin!