We have not used these in our home on clothes for stain removal, but we have used them for craft projects involving t-shirts. They work great! If you want a personalize t-shirt you can get a solid color (usually dark ones work best) and write/draw design with your bleach pen on it. After you're done just wash in the washing machine like you normally would wash your clothes and dry in the dryer. You have a super cute personalized shirt! These pens do take the color out of shirts (which it the point and how you make the personalized shirt) so I know they would take color out of other things they got on on accident. You do have to be very careful with them. The scent is pretty strong so I would recommend wearing a face mask and also some gloves. Overall I think the Clorox Bleach Pen is a great product to use in craft projects and works great! I would highly recommend it for your next personalized t-shirt project.