Benadryl Extra Strenght Itch Stopping Cream works better than any other topical itch cream I have found. I live in an area that gets lots of mosquitoes, so getting a few bites a week is pretty normal. I keep a tube of Benadryl Extra Strenght cream in my purse, one by my bed, and one in the kitchen drawer. It does a great job of stopping the itch for mosquitoe bites, ant bites, and cat scratches/reactions (I'm allergic to cats, and if I have a cut on my hand and I get near a cat it will start to swell up). This does great to stop that reaction.
However, it does have its limitations. Recently my fiance got over 175 bites on a fishing trip (we were having one of the worst mosquitoe outbreaks the area has ever seen- and he atracts mosquitoes like crazy). This cream did not cut it for that type of reaction. So it does wonders, but don't expect miracles.
But all in all, I highly recommend this cream for every day reactions (a few bites, a slight itch, etc.)
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