I switched to the ACNEdote line when I simply couldn't afford a more expensive natural brand, but to my surprise it has an even more natural ingredient list and works even better on my combination/oily face which is prone to acne during THAT time. I love that it isn't tested on animals and its natural ingredient list makes me feel comfortable about putting it on my skin. Effectiveness Don't be afraid when you see the natural ingredients listed. This stuff works like the big name brand, chemical laden cleansers I used before going natural. If I don't wash my face in the morning with ACNEdote it is oily all day long, but if I wash it the oily feeling is kept at bay until at least bedtime. Ease of Application It's a simple cleanser. All you have to do is lather and rinse. Side Effects I have not noticed any side effects since starting to use the ACNEdote line. Immediacy Nothing works right away when it comes to acne, but this works pretty quick.